Age-Specific Associations Between Adiposity and Mortality in U.S. Adults, 1999-2018.

ABSTRACT:

Background

Obesity is a leading risk factor for increased mortality. However, it remains unclear how this relationship varies across different age groups.

Objectives

The purpose of this study was to evaluate whether the associations between adiposity and mortality are modified by age in a nationally representative sample of U.S. adults.

Methods

We analyzed data from 44,041 U.S. adults aged 18 to 79 years from the National Health and Nutrition Examination Survey (1999-2018), linked to mortality data through 2019. Anthropometric measures included body mass index, waist circumference, weight, and waist-to-height ratio. Cox proportional hazards models were used to assess the interaction between age and adiposity on all-cause and cardiovascular mortality, adjusting for dem

SUBMITTER: Lu Y 

PROVIDER: S-EPMC12639814 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature