Risk of dengue following prior SARS-CoV-2 infection: a population-based cohort study.

ABSTRACT:

Background

DENV-infection and SARS-CoV-2 are now endemic in tropical regions; interactions may exist, given antigenic cross-reactivity and cross-protection. Risk of subsequent DENV-infection following prior COVID-19 was evaluated in a population-based adult cohort.

Methods

Retrospective cohort study including all Singaporeans ≥18 years. National registries were used to construct contemporaneous SARS-CoV-2-infected/test-negative cohorts from 1st Sept 2021-31st Dec 2022 during Delta/Omicron emergence. COVID-19 vaccination status was classified using the national-immunization-registry. Risk of DENV-infection recorded in the national registry 31-300 days post-COVID-19 was contrasted against test-negatives using overlap-weighted Cox regression. Risk of other infections (invasive-

SUBMITTER: Wee LE 

PROVIDER: S-EPMC12639892 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature