Prognostic value of lymphocyte-to-monocyte ratio for breast cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

The incidence of breast cancer has been ascending. The lymphocyte-to-monocyte ratio (LMR) has been reported as a prognostic factor for breast cancer. This meta-analysis aimed to assess the predictive significance of LMR in breast cancer.

Method

PubMed, Embase, Cochrane, and Web of Science were searched for relevant articles on the predictive significance of LMR in breast cancer up to May 2024. The hazard ratio (HR) of overall survival (OS), disease-free survival (DFS), recurrence-free survival (RFS), and distant metastasis-free survival (DMFS) was calculated using fixed-effects or random-effects models. The LMR threshold and follow-up information were extracted, and subgroup analyses were performed.

Result

Twenty-two studies were included in the meta-analys

SUBMITTER: Zhu L 

PROVIDER: S-EPMC12639996 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature