Low Cystatin C-to-Creatinine Estimated GFR Ratio Predicts Post-Kidney Transplant Cardiovascular Events.

ABSTRACT:

Introduction

A low cystatin C-based to creatinine-based estimated glomerular filtration rate (eGFR) ratio (eGFR_cys/eGFR_cr) is associated with poor clinical outcomes, but data in kidney transplant recipients (KTRs) remain limited. We aimed to investigate the association between low eGFR_cys/eGFR_cr and allograft loss, major adverse cardiovascular events (MACEs) and mortality, and to identify the reasons for such a low ratio.

Methods

This single-center retrospective study included KTRs with eGFR_cys/eGFR_cr determined 3 months posttransplant using the Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) and the European Kidney Function Consortium (EKFC) equations. Body composition data were obtained from a co

SUBMITTER: Moryoussef M 

PROVIDER: S-EPMC12640023 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature