Universal Exit-Site Antibiotic Prophylaxis Reduces Exit-Site Infections in Pediatric Peritoneal Dialysis.

ABSTRACT:

Introduction

Data on exit-site antibiotic prophylaxis in children undergoing peritoneal dialysis (PD) is scarce.

Methods

We conducted a prospective observational cohort study of pediatric patients (aged < 21 years) who received chronic PD 2 years before (preprophylaxis) and/or 3 years after (postprophylaxis) implementing universal exit-site antibiotic prophylaxis. Catheter and exit-site care remained unchanged. The primary outcomes were annualized rates of exit-site infection (ESI), tunnel infection (TI), and peritonitis.

Results

Fifty-seven children (32 girls; 15.1 years, interquartile range: 9.2-17.2) were included. All, except 2 patients underwent automated PD. Thirty-nine and 42 subjects, respectively, received PD during the preprophylaxis and postprophylaxis peri

SUBMITTER: Chan EY 

PROVIDER: S-EPMC12640057 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature