Pilot Randomized Trial of Dialysis Less Frequently in the Elderly: The DLITE Study.

ABSTRACT:

Introduction

The elderly represent the most rapidly growing age group with end-stage kidney disease (ESKD) world-wide. The hemodialysis (HD) prescription that provides the best outcomes for this distinct population with reduced life expectancy is unknown. The primary objective of the DLITE pilot trial was to determine the feasibility and safety of conducting a trial designed to determine whether twice versus thrice weekly HD improves quality of life (QOL) and important clinical outcomes in elderly patients with HD.

Methods

We conducted a pilot single-center open randomized controlled trial (RCT) of patients aged ≥ 70 years of age who are on incident HD. Subjects were randomized to twice (n = 20) versus thrice (n = 20) weekly HD and followed for 9 months. There

SUBMITTER: White CA 

PROVIDER: S-EPMC12640058 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature