Navigational Bronchoscopy or Transthoracic Needle Biopsy for Lung Nodules.

ABSTRACT:

Background

Each year, millions of pulmonary nodules are identified incidentally or through lung cancer screening, and many involve biopsy to distinguish cancer from benign processes. Both navigational bronchoscopy and computed tomography-guided transthoracic needle biopsy are commonly used in patients undergoing biopsies of peripheral pulmonary nodules, but the relative diagnostic accuracy of these two approaches is unclear.

Methods

In this multicenter, randomized, parallel-group, noninferiority trial, we assigned patients with an intermediate-risk or high-risk peripheral pulmonary nodule measuring 10 to 30 mm in diameter to undergo navigational bronchoscopy or transthoracic needle biopsy at seven centers across the United States. The primary outcome was diagnostic accuracy,

SUBMITTER: Lentz RJ 

PROVIDER: S-EPMC12640718 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature