Oculomotor indicators of cognitive performance are modulated by neurodegeneration.

ABSTRACT: In this study, the extent to which eye movements can be used to estimate cognitive ability in neurologically intact individuals was evaluated in the absence of clear underlying neurodegenerative processes. In contrast to previous studies of Parkinson's Disease (PD) and multiple sclerosis that demonstrated a strong link between oculomotor parameters and clinical measures of cognition, this relationship is unaffected by disease in healthy participants, enabling a more direct assessment of the connection between eye movements and cognition. Accordingly, a modest portion (≤28%) of the observed variance in cognitive test scores could be explained by oculomotor parameters in 204 participants aged 18-79 with no differences between males and females observed. The relationship between oculomotor pa

SUBMITTER: Voss P 

PROVIDER: S-EPMC12640912 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature