Global prevalence of preeclampsia, eclampsia, and HELLP syndrome: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Hypertensive disorders of pregnancy represent a leading cause of maternal and perinatal morbidity and mortality worldwide. However, prevalence estimates of preeclampsia, eclampsia, and HELLP syndrome vary considerably across studies and regions.

Objective

To determine the global prevalence of preeclampsia, eclampsia, and HELLP (Hemolysis, Elevated Liver enzymes, and Low Platelet count) syndrome, analyze their geographical distribution, and evaluate temporal and methodological trends.

Methodology

A systematic review with meta-analysis was conducted. SCOPUS, Web of Science, PubMed, and EMBASE databases were searched through May 2025. Observational studies reporting prevalence data using standardized diagnostic criteria were included. Prevalences were pooled

SUBMITTER: Vera-Ponce VJ 

PROVIDER: S-EPMC12640961 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature