Application of matrix-assisted laser desorption/ionization time-of flight mass spectrometry in clinical testing and diagnosis.

ABSTRACT: With the development of science and technology, new technologies are becoming more and more widely used in clinical testing. Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) is a technology with fast detection speed, low cost and high throughput. Since 2009, it has gradually entered the global clinical laboratory, and has gradually become an indispensable tool in clinical testing work, especially in clinical microbiology laboratory. In today's field of microbial identification, MALDI-TOF MS fingerprinting analysis has become a fast and efficient means to identify microorganisms by comparing and analyzing the fingerprint of characteristic and stably expressed proteins with the constructed common reference spectrum library at the genus and species l

SUBMITTER: Xiong Q 

PROVIDER: S-EPMC12640996 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature