Combined transversus abdominis plane and rectus sheath blocks with patient-controlled intravenous analgesia versus epidural analgesia for kidney transplantation: randomized, non-inferiority clinical trial.

ABSTRACT:

Background

Epidural analgesia can improve early postoperative recovery after renal transplantation. Abdominal wall blocks (transversus abdominis plane (TAP) and rectus sheath (RS)) combined with patient-controlled intravenous analgesia (PCIA) have also been shown to enhance postoperative recovery. However, it remains unclear whether these techniques are as effective as epidural analgesia (EP).

Methods

In this single-centre randomized non-inferiority clinical trial, participants undergoing renal transplantation were randomly assigned to receive either a TAP + RS block (combined with PCIA) or EP alone. The primary outcome was Quality of Recovery-15 (QoR-15) scores on postoperative day (POD) 1. Secondary outcomes included haemodynamics, indices of postoperative renal function,

SUBMITTER: Ning M 

PROVIDER: S-EPMC12641117 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature