Transanal versus transabdominal total mesorectal excision for rectal cancer in minimally invasive surgery: meta-analysis.

ABSTRACT:

Background

Colorectal cancer is a common malignancy. Despite advances in minimally invasive surgery, achieving optimal outcomes for locally advanced rectal cancer remains challenging. Transanal total mesorectal excision (TaTME) is an alternative to laparoscopic total mesorectal excision (LapTME), but inconsistent data warrant a comprehensive meta-analysis of the two procedures.

Methods

A systematic search was conducted across the PubMed, Embase, and Cochrane Library databases up to June 2025 using keywords related to rectal cancer and TaTME. The study protocol was registered with PROSPERO. Inclusion criteria followed the PICOS framework, selecting randomized clinical trials (RCTs) and observational studies comparing TaTME with LapTME or robotic total mesorectal excision (TME

SUBMITTER: Liao CK 

PROVIDER: S-EPMC12641135 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature