Autonomous Bayesian Optimization-Based Control System for Droplet Generation.

ABSTRACT: Droplet generation has been utilized in various applications, including drug delivery, the fabrication of functional particles, and material synthesis. Achieving the goals of these applications requires droplet generation of a desired size. Microfluidic droplet generation offers precise control of droplet dimensions. However, the flow rates of the droplet and medium phases depend on the channel configuration and properties of the working fluids, and their optimization is a labor-intensive and time-consuming process. To overcome these limitations, an autonomous Bayesian optimization (BO)-based control system for droplet generation (ABCD) is developed. In ABCD, BO is employed to inform decision-making and refine the experimental conditions. Additionally, computer vision techniques, including

SUBMITTER: Cho S 

PROVIDER: S-EPMC12641341 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature