Single-Step Patterning of Biocompatible Neural Electrodes Using Black-Pt Functionalized Laser-Induced Graphene for in Vivo Electrophysiology.

ABSTRACT: Neural electrodes are essential tools for monitoring electrophysiological activity in the brain, driving advances in neuroscience and neurotechnology. However, conventional semiconductor-based fabrication techniques suffer from high costs, complex procedures, and limited adaptability for customized designs. Here, a single-step patterning, scalable method is presented for fabricating biocompatible neural electrodes using laser-induced graphene (LIG) patterned directly onto polyimide substrates. This process requires only a standard CO₂ laser system, a spray-coated biocompatible lubricant, and black-Platinum (Pt) functionalization to form conductive traces, electrode sites, and connector pads-eliminating the need for cleanroom infrastructure or photolithography. Selective laser ab

SUBMITTER: Kim G 

PROVIDER: S-EPMC12641342 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature