Global, regional, and national burden of tracheal, bronchus, and lung cancer attributable to polycyclic aromatic hydrocarbons occupational expose from 1990 to 2021: worsening or improving?

ABSTRACT:

Background

Occupational exposure to polycyclic aromatic hydrocarbons (PAH) directly contributes to tracheal, bronchus, and lung cancer. However, it remains a challenge to accurately determine the epidemiological relationship between PAH and lung cancer.

Methods

The incidence, deaths, disability-adjusted life-years (DALYs), years lost due to disability (YLDs), years of life lost (YLLs), and corresponding estimated annual percentage changes (EAPC) were used from the Global Burden of Disease 2021. Trends were stratified by region/country, age, sex, and sociodemographic index (SDI). Joinpoint regression, decomposition analysis, and frontier analysis were conducted to explore potential characteristics of the disease burden.

Results

The burden of occupational PAH exposure i

SUBMITTER: Wu X 

PROVIDER: S-EPMC12641943 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature