Comparative efficacy of multiple drugs for non-alcoholic fatty liver disease: a Bayesian network meta-analysis.

ABSTRACT:

Background

Non-alcoholic fatty liver disease (NAFLD), now referred to as metabolic dysfunction-associated steatotic liver disease (MASLD), is the most prevalent chronic liver disease worldwide. However, it remains unclear which drug treatment is more effective. Therefore, we conducted a network meta-analysis to comprehensively compare the efficacy of several potentially beneficial hypoglycemic drugs and vitamin E in treating patients with NAFLD.

Methods

This Bayesian network meta-analysis searched PubMed, Embase, Web of Science, and the Cochrane Library for randomized controlled trials (RCTs). We employed random-effects models to calculate mean differences (MD), relative risk (RR), and 95% confidence intervals (CI). The study outcomes included anthropometric measurements, bi

SUBMITTER: Xiao Z 

PROVIDER: S-EPMC12642067 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature