Neurodevelopmental delays in children born after medically assisted reproduction: a national population cohort study.

ABSTRACT:

Background

Importance: The neurodevelopmental outcomes of children born after medically assisted reproduction remain incompletely characterized on a population level. We were to assess the incidence and relative risk of neurodevelopmental delay in the children of infertile women born after unassisted conception, intrauterine insemination (IUI), and in vitro fertilization (IVF).

Method

We conducted a retrospective cohort study using the National Health Insurance Service database of South Korea from October 2017 through December 2023. The study included 115 839 singleton, full-term, non-low-birthweight children born to women aged 20-49 years with a diagnosis of female infertility. The exposure was mode of conception-spontaneous, IUI, or IVF-balanced by propensity score matchin

SUBMITTER: Choe SA 

PROVIDER: S-EPMC12642093 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature