Association between vascular overload index and arterial stiffness: a secondary analysis of a nationwide cross-sectional study in Japan.

ABSTRACT:

Background

Current evidence regarding the association between vascular overload index (VOI) and arterial stiffness in Japanese adults remains limited. Given that brachial-ankle pulse wave velocity (baPWV) has been established as a validated biomarker for assessing atherosclerosis, this study aims to comprehensively investigate the association between VOI and arterial stiffness through baPWV measurements.

Methods

This secondary analysis utilized health examination data from 912 participants (2004-2012) at Gifu Murakami Memorial Hospital, Japan. The baseline data of participants were divided into four groups according to the quartiles of VOI for comparative analysis. Univariate linear regression and multivariable linear regression were used to investigate the association betwe

SUBMITTER: Liu Y 

PROVIDER: S-EPMC12642175 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature