Ocular manifestations of primary thrombotic microangiopathies : a descriptive systematic review.

ABSTRACT:

Background

Primary thrombotic microangiopathies (TMAs) include Thrombotic Thrombocytopenic Purpura (TTP) and Hemolytic Uremic Syndrome (HUS), which may cause ocular signs that need to be detected and managed accordingly. Therefore, we aim to identify the ocular manifestations caused by the systemic effects of primary TMAs, including HUS and TTP.

Methods

We searched PubMed, Scopus, and Web of Science databases from inception until March 2024. We included case reports, case series, and retrospective reviews reporting ocular manifestations of primary HUS or TTP. We excluded experimental studies, papers written in a language other than English, studies that included patients with secondary TTP or HUS, pregnant patients, patients with ocular trauma or surgery, and patients with o

SUBMITTER: Baker M 

PROVIDER: S-EPMC12642294 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature