A patient-specific, 3D printed neurostimulator enabling focal transcranial electrical stimulation and EEG at home.

ABSTRACT:

Background

The therapeutic potential of non-invasive transcranial electric stimulation (tES) is growing, but challenges in tailoring treatments to individual patients persist. We demonstrated that personalized montages, informed by biophysical modeling, can reduce dose variability and improve target engagement. However, traditional setups are prone to electrode placement errors, leading to inconsistent dosage, localization and potential off-target engagement.

Methods

We developed a pipeline for creating patient-specific 3D-printed caps based on individual MRI scans to allow custom placement of up to 34 electrodes. Hybrid brush electrodes were incorporated to facilitate the use on with-hair regions of the head. The patient-specific caps are integrated within a Neurostimulator

SUBMITTER: Joodaki M 

PROVIDER: S-EPMC12642300 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature