Multivariate environmental exposures are reflected in whole-brain functional connectivity and cognition in youth.

ABSTRACT: Each individual's complex, multidimensional environment, known as their "exposome", plays an essential role in shaping cognitive neurodevelopment. Understanding the mechanisms whereby children's exposome influences their development is crucial to facilitate the design of interventions to foster positive developmental trajectories for all youth. Recent work has identified a general exposome factor associated with socio-economic inequality that is strongly related to cognition and individual differences in the spatial organization of functional brain networks in youth. Building on these findings, the current study explores whether alterations in functional connectivity may represent a potential mechanism linking variation in the exposome to cognitive performance. We apply a data-driven, cros

SUBMITTER: Lichenstein SD 

PROVIDER: S-EPMC12642680 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature