Mind's eye: Saccade-related evoked potentials support visual encoding in humans.

ABSTRACT: In active vision, the brain receives and encodes discontinuous streams of visual information gated by saccadic eye movements. Saccadic modulation of neural activity is hypothesized to evolve to support perception and memory; however, it remains unclear whether this mechanism exist in humans, and potential functional roles have not been determined. We used eye tracking and intracranial local field potentials recorded from invasively monitored epilepsy patients when they performed visual encoding tasks, and observed consistent evoked potentials following saccades (saccade-related evoked potentials, SREPs) across the cerebrum. These SREPs were not attributable to ocular muscle activity or retinal input. Their magnitudes were not explained by spatial proximity to eye muscles or saccade eccentr

SUBMITTER: Tan G 

PROVIDER: S-EPMC12642748 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature