Effects of virtual reality intervention dosage on gait performance in Parkinson's disease: a systematic review and meta-analysis.

ABSTRACT:

Objective

Gait impairment is a prevalent and disabling feature of Parkinson's disease (PD) that is often insufficiently improved by conventional rehabilitation approaches. Virtual reality (VR)-based training has emerged as a novel therapeutic strategy; however, the overall efficacy of VR interventions on gait outcomes in PD remains inconclusive. This systematic review and meta-analysis aimed to (1) quantify the effects of VR-based rehabilitation on gait performance in individuals with PD, and (2) investigate whether treatment outcomes are moderated by intervention dosage parameters-such as training frequency, session duration, and total intervention period-as well as patient-related factors like disease duration and age.

Methods

Seven databases (Embase, Web of Science, PubMe

SUBMITTER: Yu S 

PROVIDER: S-EPMC12642915 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature