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ABSTRACT: Introduction
Ventilator-associated pneumonia (VAP) is a significant source of morbidity and mortality. We sought to assess the current evidence on antimicrobial-coated endotracheal tubes (ETT) as one potential tool to break the cycle of colonization and infection among ICU patients.Methods
We conducted a narrative review of available studies focused on the use of antimicrobial-coated ETTs to reduce VAP. The selection process adhered to PRISMA-ScR guidelines.Results
A total of 58 studies met the inclusion criteria. Silver-based coatings were the most common, with 15 studies, including three randomized controlled trials and two systematic reviews. Of the 15 studies, 12 demonstrated a reduction in bacterial colonization. Two demonstrated delay of VAP onset and three de
SUBMITTER: Richardson AK
PROVIDER: S-EPMC12643042 | biostudies-literature | 2026 Feb
REPOSITORIES: biostudies-literature