Green "turn-off" luminescent nanosensor for the sensitive analysis of finerenone in various matrices: application of recent greenness assessment techniques.

ABSTRACT: Finerenone (FNR) is an innovative FDA-approved selective non-steroidal mineralocorticoid receptor antagonist utilized in kidney failure. This study utilizes eco-friendly nitrogen and sulfur co-doped carbon quantum dots (N,S-CQDs), fluorescent nanomaterials, to introduce a sensitive and environmentally sustainable spectrofluorometric platform for the analysis of FNR. Water-soluble N,S-CQDs were prepared from green precursors (citric acid and glutathione) using a straightforward and eco-friendly hydrothermal technique. The intrinsic fluorescence of the fluorophore was monitored at λ _em = 419 nm upon excitation at 344 nm. The luminescence of the fluorophore was quantifiably dropped after the incorporation of FNR, which is the foundation of this luminescent technique. The lum

SUBMITTER: Ali MB 

PROVIDER: S-EPMC12643135 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature