Physical Domains, Access to Kidney Transplantation, and Waitlist Mortality.

ABSTRACT:

Background

Frail kidney transplant (KT) candidates, characterized by low physical activity/function, have decreased chances of listing and increased risk of waitlist mortality. Impairments in these physical domains contribute to perceived physical burden and may exacerbate one another. Further, understanding the association of each domain individually with adverse outcomes may improve pre-KT risk stratification.

Methods

We leveraged 2708 KT candidates (age ≥ 18) from a two-center prospective cohort study (2014-2024). We assessed physical activity (Minnesota Leisure Time Physical Activity Questionnaire), physical function (gait speed), and physical burden (10 questions from the Kidney Disease Quality of Life Short Form) at evaluation. We quantified the association of these th

SUBMITTER: Huang NS 

PROVIDER: S-EPMC12643171 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature