Association Between Industrialized Dietary Pattern and Cardiometabolic Risk Factors in Children With FTO RS9939609 Gene Polymorphism.

ABSTRACT: Dietary patterns may increase cardiometabolic risk, especially in genetically predisposed individuals. Thus, the present study evaluated the association between dietary patterns and cardiometabolic risk factors in children with fat mass and obesity associated (FTO) gene polymorphism. A cross-sectional survey of 258 children aged 4-7 years. Body composition was determined with dual-energy x-ray absorptiometry (DEXA). Biochemical samples and blood pressure were analyzed. Genotyping of rs9939609 was performed using oral swab samples and the TaqMan SNP test. Multiple linear regression stratified by FTO gene categories analyzed the association between dietary patterns and cardiometabolic risk factors. The prevalence of polymorphism was 20.2%. Five dietary patterns were identified: "Traditional"

SUBMITTER: Kiepper BHDLP 

PROVIDER: S-EPMC12643185 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature