Probiotics in nonsurgical treatment of peri-implant diseases: A systematic review & meta-analysis.

ABSTRACT:

Background

Peri-implant disease is an inflammatory condition that affects implant stability and quality of life. As nonsurgical treatments show limited efficacy, probiotics have been explored for their anti-inflammatory effects. This systematic review evaluated the efficacy, safety, and health-related quality of life outcomes of peri-implant diseases.

Methods

Databases were searched for randomized controlled trials (RCTs) and non-randomized studies (November 2024). The outcomes included bleeding on probing (BoP), probing depth, plaque index, and biomarkers. The protocol was registered with International Prospective Register of Systematic Reviews (CRD42024617103). The RoB in RCTs was assessed using the Cochrane Risk of Bias 2.0 tool, and non-RCTs using the RoB In Non-randomiz

SUBMITTER: AlRowis R 

PROVIDER: S-EPMC12643619 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature