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Exophiala infection: A systematic review.


ABSTRACT:

Background

Given the limited understanding of this rare fungal disease, this study aimed to conduct a systematic review of patients with Exophiala infections.

Methods

A systematic retrospective analysis was performed, including 248 articles involving 298 patients, retrieved from PubMed and China National Knowledge Infrastructure. Statistical analyses were conducted using the Chi-square test and binary logistic regression by SPSS 27.0.

Results

A total of 19 Exophiala species were identified, with E dermatitidis, E jeanselmei, and E spinifera being the most prevalent. Common infection sites included subcutaneous tissue, lung, and skin, with distinct site predilections among different species. Central nervous system (CNS) infection was the only independent risk factor fo

SUBMITTER: Xue S 

PROVIDER: S-EPMC12643661 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature