The association of triglyceride-glucose index and related indices with all-cause and cardiovascular mortality in biologically aging populations.

ABSTRACT: The relationship between the triglyceride-glucose index (TyG) and all-cause and cardiovascular mortality in biological aging (BA) populations remains unclear. This study aimed to investigate the role of TyG and its derived indices (TyG-Body Mass Index [TyG-BMI] and TyG-Waist-to-Height Ratio [TyG-WHtR]) as potential biomarkers of mortality risk in biologically aging populations. This study included participants from the National Health and Nutrition Examination Survey database between 1999 and 2018 and constructed 3 metabolism-related indices: TyG, TyG-BMI, and TyG-WHtR. Kaplan-Meier survival curves, Cox regression analysis, trend tests, and restricted cubic splines were used to assess the relationship between TyG-related indices and all-cause and cardiovascular mortality in BA populations

SUBMITTER: Cheng MQ 

PROVIDER: S-EPMC12643700 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature