A Nomogram for Predicting Lung Metastasis in Papillary Thyroid Cancer Patients Aged Less Than 55 Years.

ABSTRACT:

Highlights

A nomogram predicting lung metastasis in patients with papillary thyroid cancer was developed and validated. Our study focused on patients under 55 years old, revealing the genetic factors linked to lung metastasis in this younger group. Young patients with the BRAF V600E mutation are less likely to develop lung metastasis.

Objective

To develop and validate a nomogram for predicting the risk of lung metastasis in patients under 55 years old with papillary thyroid cancer (PTC).

Methods

A total of 243 patients under 55 years old with PTC were retrospectively collected from January 2017 to June 2020 and randomly divided into a training group (n = 170) and a validation group (n = 73) in a 7:3 ratio. Genetic testing data and clinical information were compiled, a

SUBMITTER: Yang H 

PROVIDER: S-EPMC12643860 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature