Metagenomic analysis of gut microbiota composition and function in wild mice (<i>Rattus flavipectus</i>) infected with <i>Enterocytozoon bieneusi</i>.

ABSTRACT:

Background

Enterocytozoon bieneusi (E. bieneusi) is a pathogenic microsporidian that infects a variety of hosts, including wild mice, potentially influencing their gut microbiota. This study aims to explore how E. bieneusi infection influences the gut microbiota composition and function in wild mice.

Methods

Fecal samples were collected from 20 wild mice (Rattus flavipectus) in September 2023 in Yunnan Province, China. The PCR results showed that 10 were infected with E. bieneusi and 10 were uninfected, with no samples testing positive for Cryptosporidium spp., Blastocystis, Giardia, Cyclospora or Balantioides coli. DNA was extracted and subjected to metagenomic sequencing using Illumina HiSeq. Gut microbiota composition was a

SUBMITTER: Yu HL 

PROVIDER: S-EPMC12643989 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature