Severe mitral valve papillary muscle rupture of isolated Whipple's endocarditis: a case report and review of the literature.

ABSTRACT:

Background

Tropheryma whipplei endocarditis (TWE) is rarely reported. Diagnosis is particularly challenging when it occurs as isolated TWE without classical manifestations of Whipple's disease.

Case presentation

A 35-year-old Asian female with systemic lupus erythematosus presented with acute heart failure secondary to mitral valve papillary muscle rupture as her sole symptom, requiring emergent veno-arterial extracorporeal membrane oxygenation support and urgent valve replacement. Intraoperative absence of vegetations and negative conventional microbiological examination preliminarily ruled out infective endocarditis. However, on postoperative day (POD) 3, her condition rapidly deteriorated into septic shock. Follow-up chest CT revealed bilateral asymmetric pulmonary

SUBMITTER: Shi Y 

PROVIDER: S-EPMC12644038 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature