Expression of dementia biomarkers in Appalachian and non-Appalachian ELVO patients during thrombectomy.

ABSTRACT:

Background/context

Vascular Cognitive Impairment and Dementia (VCID) affects 25-30% of stroke patients and includes cognitive impairments caused by vascular injury, such as post-stroke dementia. Rehabilitation has the potential to improve the quality of life for patients at risk of developing dementia. However, there is currently no reliable method to identify those at risk of dementia after a stroke. Several biomarkers, including ADRD (Alzheimer's disease and related dementias) biomarkers (Ab, tau, NfL, and GFAP) and angiogenic factors (VEGF, Flt-1, Tie-2, PIGF, and FGF) have been associated with the development of dementia.Populations in Appalachia experience a higher incidence of stroke and related mortality compared to other groups. Given the elevated stroke rates in Appalachia

SUBMITTER: Anil N 

PROVIDER: S-EPMC12644046 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature