Lipid accumulation product and visceral adiposity index in women with and without polycystic ovary syndrome: a systematic review and meta-analysis.

ABSTRACT:

Background

Polycystic ovary syndrome (PCOS) is a chronic, heterogeneous and prevalent endocrine-metabolic condition.

Objectives

This study aims to synthesize the available evidence on the comparison of lipid accumulation product (LAP) and visceral adiposity index (VAI) in women with and without PCOS.

Design

Systematic review and meta-analysis.

Data sources and methods

A systematic search was executed across five electronic databases. Continuous variables were assessed using the standardized mean difference (SMD) and its 95% confidence interval (CI).

Results

A total of 46 studies were included (n = 12,442). PCOS patients have higher values of LAP (n = 10,658; SMD: 0.65; 95% CI: 0.47-0.83, p < 0.05; I ² = 93.65%) and

SUBMITTER: Ulloque-Badaracco JR 

PROVIDER: S-EPMC12644441 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature