Correlation of red cell distribution width with depression among adults with and without self-reported history of cancer.

ABSTRACT: Red blood cell distribution width (RDW), recognized as a biomarker for systemic inflammation and oxidative stress, has been associated with various health outcomes, including depression. However, the precise relationship between RDW and depression, particularly in individuals with differing cancer statuses, remains ambiguous. In this cross-sectional study, data from 32,467 adults aged 18 and older from the NHANES 2005-2018 cohort were analyzed. Depressive symptoms were evaluated using the Patient Health Questionnaire-9 (PHQ-9), where a score of 10 or above indicated moderate-to-severe depression. Multivariate logistic regression models assessed the association between RDW and depression, accounting for demographic, lifestyle, clinical, and laboratory covariates. Subgroup analyses considere

SUBMITTER: Li Y 

PROVIDER: S-EPMC12644650 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature