Differences in the risk association of TERT rs2736098 (C > T) with lung cancer between Caucasian and Asian populations: A meta-analysis.

ABSTRACT: The T allele variant of TERT rs2736098 has been associated with an increased risk of lung cancer (LC), yet various studies have yielded inconsistent findings. The purpose of this study is to verify the association between the rs2736098 variant and LC risk, as well as to investigate the differences in this association across different ethnic groups (Caucasians and Asians), various LC subtypes, and distinct smoking statuses. A computer search was conducted for literatures published up to December 20, 2024, in PubMed, Embase, Web of Science, and MEDLINE databases. Data were analyzed using RevMan 5.3, while sensitivity analysis and publication bias were assessed using Stata 14.0. The stability of the results was evaluated with TSA software Registration number: CRD420251030755. The T allele var

SUBMITTER: Wu X 

PROVIDER: S-EPMC12644772 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature