Assessment of fetal lung maturity and prediction of neonatal respiratory distress syndrome by MV-Flow imaging.

ABSTRACT:

Purpose

Neonatal respiratory distress syndrome (NRDS) is a leading cause of morbidity in preterm infants. Existing prenatal tests for fetal lung maturity are either invasive or insufficiently reliable. Microvascular flow imaging (MV-Flow) is a novel Doppler ultrasound technique capable of detecting low-velocity microvascular flow. This study evaluated its utility for visualizing fetal pulmonary microcirculation and predicting NRDS risk.

Methods

A prospective, two-part study was conducted. In part 1, 167 normal singleton pregnancies (12-42 weeks) underwent MV-Flow imaging of the fetal lungs. The vascular intensity of microvascular volume (VIMV) was measured using different regions of interest and compared with conventional Doppler; reproducibility and gestational-age trends w

SUBMITTER: Wang Q 

PROVIDER: S-EPMC12644970 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature