Quinoa Ameliorates High-Fat Diet-Induced Obesity in Female Mice by Regulating Gut Microbiota and Adipogenesis.

ABSTRACT: The female obesity epidemic remains a major global public health challenge, with limited effective treatments available. Daily dietary management serves as an effective strategy for obesity prevention. As a promising functional food, quinoa has been demonstrated to possess anti-obesity properties. However, the mechanisms of quinoa on high-fat diet (HFD)-induced female obesity and its role in regulating adipose tissue remain unclear. In the present study, the effects of different dosages of quinoa on obesity and its underlying mechanisms were investigated in an HFD-induced mouse model of obesity. Six-week-old female C57BL/6J mice were fed an HFD to induce obesity, followed by an 8-week intervention with low dosage of quinoa (LQ), medium dosage of quinoa (MQ), and high dosage of quinoa (HQ),

SUBMITTER: Liu Y 

PROVIDER: S-EPMC12645152 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature