Co-Occurring Conditions and Sleep Symptoms Associated With Obstructive Sleep Apnea in Children With Down Syndrome.

ABSTRACT:

Background and objectives

Sleep disordered breathing (SDB) is prevalent in children with Down syndrome (DS). The American Academy of Pediatrics recommends that all children with DS undergo a polysomnogram between 3 and 4 years of age irrespective of symptoms. Our objective is to describe the clinical symptoms and breathing patterns of children with DS based on their polysomnogram results.

Methods

A large, single-center retrospective study evaluated SDB in children with DS at moderate altitude between 1642 and 2087 m above sea level. The primary outcome was obstructive apnea hypopnea index (OAHI). Secondary outcomes included central apnea index (CAI), gas exchange, sleep symptoms, and co-occurring condition(s). Associations between OSA severity and caregiver-reported sleep sy

SUBMITTER: Curry TA 

PROVIDER: S-EPMC12645186 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature