Molecular responses in abdominal subcutaneous adipose tissue after a session of endurance exercise: effects of exercise intensity.

ABSTRACT: The primary aim of this study was to compare the acute effects of three exercise intensities on abdominal subcutaneous adipose tissue (aSAT) transcriptome in regular exercisers. A total of 45 adults who exercise regularly were assigned to perform a single session of either low-intensity continuous (LOW; 60 min at 30% VO₂max; n = 15), moderate-intensity continuous (MOD; 45 min at 65% VO₂max; n = 15) or high-intensity interval exercise (HIGH; 10 × 1 min at 90% VO₂max interspersed with 1 min active recovery; n = 15). aSAT biopsy samples were collected before and 1.5 h after the exercise session for bulk RNA sequencing and targeted protein immunoassays. HIGH upregulated genes were involved in angiogenesis, protein secretion and insulin signalling pathways, wher

SUBMITTER: Ahn C 

PROVIDER: S-EPMC12645526 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature