Disease burden due to respiratory syncytial virus infection among under-5 children of India for 2020: a multiplicative model using meta-estimates.

ABSTRACT:

Background

Respiratory syncytial virus (RSV) is an important cause of acute lower respiratory infections (ALRI) among under-5 (U5) children. Generating evidence on disease burden is important to inform decisions regarding RSV preventive strategies. This systematic analysis estimated RSV-associated burden in U5 children for 2020 in India and identified data needs for decision-making regarding preventive strategies.

Methods

We conducted meta-analyses of published studies from India between January 2000 and July 2021 and used multiplicative models by applying ALRI and RSV meta-estimates to population estimates for 2020 and national pneumonia deaths. Uncertainty ranges (UR) were calculated using Monte Carlo simulations.

Results

Using 36 eligible studies including unpublis

SUBMITTER: Joseph J 

PROVIDER: S-EPMC12645627 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature