The LoaD study: the association between different types of physical activity and the progression of knee osteoarthritis-a cohort study protocol.

ABSTRACT:

Background

The global prevalence of osteoarthritis (OA) is expected to rise as the population ages, leading to increased physical impairments that often reduce physical activity. Knee OA, in particular, is a leading cause of chronic pain and disability in people over 40. OA progression varies among individuals, with factors such as higher age and body mass index contributing to a more rapid progression. However, research suggests that engaging in physical activity such as hiking and running may help alleviate pain and slow OA progression. However, current literature on the relationship between physical activity and knee OA is largely retrospective, lacks comparative analyses across different physical activity types and rarely considers the intensity of physical activity. To address

SUBMITTER: van der Voort JW 

PROVIDER: S-EPMC12645648 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature