Associations between sulfur dioxide exposure and mortality, with a focus on cardiovascular disease: a multi-county time series analysis in central China.

ABSTRACT:

Background

Despite growing evidence on health effects associated with atmospheric pollutants, limited research has investigated the effect of ambient sulfur dioxide (SO₂) on disease-specific mortality, particularly cardiovascular disease (CVD).

Methods

We evaluated the effect of SO₂ on CVD mortality in 122 counties, Hunan Province, Central China, during the period 2018-2022. Daily mortality records and ambient air pollution concentrations were collected, and time-series regression models combined with multilevel meta-analyses were utilized for data analysis.

Results

A total of 2.21 million all-cause deaths were recorded, with CVD accounting for 1.15 million cases. The annual average SO₂ concentration exhibited a significant decline, de

SUBMITTER: Lv LS 

PROVIDER: S-EPMC12645791 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature