Computational inference of Rhizobium phaseoli transcriptional regulatory network predicts Transcription Factors involved in nodulation.

ABSTRACT: Growth of the common bean plant Phaseolus vulgaris is tightly linked to its symbiotic relationship with diverse rhizobial species, particularly Rhizobium phaseoli, an alphaproteobacterium that forms root nodules and provides high levels of nitrogen to the plant. Molecular cross-talk is known to happen through plant-derived metabolites, but only flavonoids have been identified as nodulation signals, which act through the activation of the NodD Transcription Factor (TF). The identification of signals that mediate nodulation via TFs can aid in the rational design of biofertilizers that promote plant-bacteria symbiosis. Here, we identified 57 TFs in the R. phaseoli genome through sequence conservation from Escherichia coli, and predicted a transcriptional regulatory network comprising 16 TFs,

SUBMITTER: Hernandez-Benitez EM 

PROVIDER: S-EPMC12645834 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature