MicroRNA response in insect salivary glands to plant virus infection.

ABSTRACT: Most arboviruses rely on insect vectors for transmission, with salivary glands serving as a critical gateway for viral spread to new hosts. MicroRNAs (miRNAs) are key regulators of gene expression, yet their roles in salivary glands during virus infection remain poorly understood. Using the small brown planthopper (SBPH)-rice stripe virus (RSV) system, we sequenced small RNAs from salivary glands of nonviruliferous and viruliferous insects and identified 5,909 known miRNAs from 201 families. Of these, 1,143 miRNAs were differentially expressed upon RSV infection, including 1,090 upregulated from 36 families and 53 downregulated from 11 families. These differentially expressed miRNAs were predicted to target 2,876 genes. Gene Ontology analysis showed that targets of upregulated miRNA were e

SUBMITTER: Xiao Y 

PROVIDER: S-EPMC12646003 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature