Analysis of gap times based on panel count data with informative observation times and unknown start time.

ABSTRACT: In biomedical studies, one is often interested in repeat events with longitudinal observations occurring only intermittently, resulting in panel count data. The first stage of labor, measured through unit-increments of cervical dilation in pregnant women, provides such an example. Obstetricians are interested in assessing the gap time distribution of per-unit increments of cervical dilation for better management of labor process. Typically, only intermittent medical examinations for cervical dilation occur after (already dilated) women get admitted to hospital. The observation frequency is very likely correlated to how fast/slow she dilates. Thus one could view such data as panel count data with informative observation times and unknown start time. Here, we propose semiparametric proportio

SUBMITTER: Ma L 

PROVIDER: S-EPMC12646053 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature