Bronchoscopic management of airway fistulas: a clinical analysis of 45 cases with integrated bioinformatic analysis.

ABSTRACT:

Background

Airway fistula represents a complex clinical condition where the optimal bronchoscopic management remains controversial. This study aims to evaluate clinical characteristics, bronchoscopic treatment efficacy, and prognostic factors.

Methods

This retrospective study analysed 45 patients with fistulas who underwent a total of 56 bronchoscopic intervention sessions over the past seven years. The fistulas were categorized and analysed based on their size, clinical features and treatment efficacy, with prognostic factors for healing being evaluated. In parallel, a bioinformatic analysis was initiated with 2075 genes sourced from GeneCards. Following filtration, the top 20 hub genes were identified and subsequently subjected to pathway enrichment analysis to elucidate t

SUBMITTER: Sun W 

PROVIDER: S-EPMC12646086 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature