A standards-based approach to digital health research: implementing the people heart study.

ABSTRACT:

Objective

To assess whether HL7 Fast Healthcare Interoperability Resources (FHIR) can underpin a fully standards-based, end-to-end digital research architecture, demonstrate it in a live study, and quantify its benefits for interoperability and development efficiency.

Materials and methods

We designed a generalizable standards-based architecture to accelerate digital health research relying on FHIR as the sole transactional model throughout a participant research lifecycle starting from API-based study discovery to results. It was instantiated for People Heart Study, a real-world digital health cardiovascular-risk assessment study with its protocol transformed into FHIR resources (eligibility, consent, tasks, and results). Evaluation examined workflow coverage, validator con

SUBMITTER: Sayeed R 

PROVIDER: S-EPMC12646378 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature