Study of changes in brain dynamics during sleep cycles in dogs under effect of trazodone.

ABSTRACT: Sleep is a fundamental biological process essential for cognitive function, memory consolidation, and overall health in both humans and animals. Dogs, in particular, share many physiological and neurological similarities with humans, making them a valuable model for sleep research. Similar to humans, dogs can experience sleep disorders that disrupt sleep cycles and impair cognitive function. While serotonin antagonist and reuptake inhibitors (SARIs), like trazodone, have been shown to alleviate these conditions in dogs, their underlying neural mechanisms remain poorly understood. This study investigates the effects of trazodone on brain dynamics in healthy dogs using electroencephalographic (EEG) analysis. We compared treated subjects with a control group by characterizing EEG activity acr

SUBMITTER: Catanzariti M 

PROVIDER: S-EPMC12646450 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature